Italija – Mokslinių tyrimų ir taikomosios veiklos paslaugos bei su jomis susijusios konsultacinės paslaugos – Evaluation of microbiome-relevant biomarkers and in vitro models for xenobiotic risk assessment
Italija – Mokslinių tyrimų ir taikomosios veiklos paslaugos bei su jomis susijusios konsultacinės paslaugos – Evaluation of microbiome-relevant biomarkers and in vitro models for xenobiotic risk assessment
I dalis: Perkančioji organizacija
I.1) Pavadinimas ir adresai:
Oficialus
pavadinimas: European Food Safety Authority
Adresas: Via Carlo Magno 1A
Miestas: Parma
Pašto
kodas: I-43126
Šalis: Italija
Asmuo
ryšiams:
El-paštas: efsaprocurement@efsa.europa.eu
Interneto adresas (-ai):
Pagrindinis adresas: https://www.efsa.europa.eu
II dalis: Objektas
II.1.1) Pavadinimas:
Evaluation of microbiome-relevant biomarkers and in vitro models for xenobiotic risk assessment
Nuorodos numeris: EFSA/2026/OP/0008-PIN
II.1.2) Pagrindinis BVPŽ kodas:
73000000
Mokslinių tyrimų ir taikomosios veiklos paslaugos bei su jomis susijusios konsultacinės paslaugos
II.1.3) Sutarties tipas:
Kita
II.1.4) Trumpas aprašymas:
Addressing a key knowledge gap identified in EFSA's Gut Microbiome Roadmap, the project aims to establish foundational methodological elements for assessing the potential adverse effects of dietary xenobiotics on the gut microbiome and host health through systematic available evidence appraisal and meta-synthesis. In particular, the project will systematically evaluate promising microbiome-relevant biomarkers related to key health endpoints (e.g. intestinal barrier integrity, inflammatory responses, microbiome metabolic capacity, immune system effects, microbiome composition and function) and the suitability of available in vitro models (e.g., SHIME, triple co-culture, MBRA, organoids). It will prioritise optimal biomarker-in vitro model pairings based on regulatory science applicability and feasibility, and identify appropriate analytical methods (including omics-based approaches) for each combination. The outcomes will provide an evidence-based prioritisation framework and feasibility assessment to inform potential follow-up experimental validation of the prioritised biomarker-in vitro model combinations and support the possible integration of microbiome data into risk assessment.
II.2) Aprašymas:
II.2.1) Kitas (-i) šio pirkimo BVPŽ kodas (-ai):
73000000 Mokslinių tyrimų ir taikomosios veiklos paslaugos bei su jomis susijusios konsultacinės paslaugos